Abstract di un ulteriore articolo pubblicato sulla rivista scientifica Epidemiology di questo Luglio (www.epidem.com).


Esso si riferisce ad uno studio condotto in Svezia fra lavoratori di industrie di ingegneria comprendente 537.692 uomini e 180.529 donne.
E' risultato che il rischio di morbo di Alzheimer come causa primaria di morte o come concausa aumenta al crescere dell'esposizione ai campi elettromagnetici a frequenza estremamente bassa sia fra gli uomini e sia fra le donne, con un rischio relativo di 4 volte il valore atteso nel gruppo con livello di esposizione più elevato.

Per lo stesso gruppo di livello di esposizione è risultato un rischio relativo di Sclerosi Laterale Amiotrofica (ALS) di 2.2 volte il valore atteso suggerendo una relazione dose-risposta.

Non è stato evidenziato un maggior rischio per il morbo di Parkinson o la sclerosi multipla.

Valerio Gennaro medici per l'ambiente
Neurodegenerative Diseases in Welders and Other Workers Exposed to High Levels of Magnetic Fields Niclas Håkansson * ; Per Gustavsson; Christoffer Johansen
Birgitta Floderus

Background:
Previous work has suggested an increase in risk of amyotrophic lateral sclerosis (ALS) and Alzheimer's disease among workers exposed to extremely low-frequency magnetic fields (ELF-MF). We evaluated the relation between ELF-MF from occupational exposures and mortality from neurodegenerative diseases

Methods:
The study was based on a cohort of Swedish engineering industry
workers, comprising 537,692 men and 180,529 women. The cohort was matched against the 3 most recent censuses and The Causes of Death Registry. Levels of ELF-MF exposure were obtained by linking occupation according to the censuses to a job exposure matrix. We used 4 levels of exposure and considered both the primary and contributing causes of death, 1985-96.

Results:
The risk of Alzheimer's disease as primary or contributing cause of death increased with increasing exposure to ELF-MF among both men and women, with a relative risk (RR) of 4.0 and a 95% confidence interval (95% CI) of 1.4-11.7 in the highest exposure group for both sexes combined. There was a RR of 2.2 (95% CI: 1.0-4.7) for ALS in the highest exposure group with the suggestion of an exposure-response relationship. No evidence of increased risk was seen for Parkinson's disease or multiple sclerosis.

Conclusions:

The findings support previous observations of an increased risk of Alzheimer's disease and ALS among employees occupationally exposed to ELF-MF. Further studies based on morbidity data are warranted.

Key Words Alzheimer's disease; Amyotrophic Lateral Sclerosis; Electromagnetic Fields; Neurodegenerative Disease; Occupation

 From the

*Institute of Environmental Medicine, Karolinska Institutet
Stockholm, Sweden,


National Institute for Working Life, Solna, Sweden, Department of Occupational and Environmental Health, Stockholm Public Health Center, Stockholm, Sweden, Division of Occupational Health, Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden Institute of Cancer Epidemiology, Danish Cancer societày,

Copenhagen, Denmark

This work was supported by grant from ELFORSK, Sweden. Address correspondence to:
Niclas Håkansson, Institute of Environmental Medicine, Karolinska Institutet, Box 210, S-171 77 Stockholm, Sweden. Tel: +46 8 728 70 80, Fax: +46 8 30 45 71.

E-mail: Questo indirizzo email è protetto dagli spambots. È necessario abilitare JavaScript per vederlo.. Submitted 12 March 2002;

final version accepted 12 November 2002.  Epidemiology 2003; 14(4):420-426 Copyright © 2003 Lippincott Williams & Wilkins
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